Distribution of Human Papilloma Virus (HPV) in Cervical Adenocarcinoma and Adenosquamous Carcinoma

Approximately 20-30% of all cervical cancer cases are adenocarcinoma and adenosquamous carcinoma. Around 70% these types related to infection Human Papillomavirus (HPV). This study evaluated the distribution HPV genotype in A cross-sectional was conducted at Department Anatomic Pathology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January December 2015. The sample were 22 formalin-fixed paraffin-embedded (FFPE) tissues carcinoma tissues. FFPE used for DNA extraction followed with genotyping detect 40 genotypes HPV, including low risk (LR) high (HR) HPV. histopathological adenocarcinomas NOS mucinous adenocarcinoma, while glassy. All specimens infected by In 6, 11, 16, 18, 31, 45, 68B, 72, 59. 18 predominant, which found 13/22 (59.1%) 19/22 (86.4%) Single multiple infections 9/22 (40.9%), 21/22 (95.5%) 1/22 (4.5%) respectively. most common HR HPVs this 16 LR 6.